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No must, mold, mildew, or rust issues?
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No not ever. Constant air flow system will not allow moisture to form. Small metal parts that are exposed to heat seem to be the only exception. I use a metal protector on these parts prior to storage, a small artist's brush dipped in the protector (then touch up the affected areas) seems to work just fine.
Otherwise like everyone else says the car comes out like it goes in you just have to be sure you have constant air flow in and out of the bubble. I have two capsules in service - currently one capsule in service for 10 years - with two fan motor replacements.